Broad-Spectrum Inhibition of Respiratory Virus Infection by MicroRNA Mimics Targeting p38 MAPK Signaling

• Main Authors: Jana L. McCaskill (Author), Sarah Ressel (Author), Andreas Alber (Author), Jane Redford (Author), Ultan F. Power (Author), Jürgen Schwarze (Author), Bernadette M. Dutia (Author), Amy H. Buck (Author)
• Format: Book
• Published: Elsevier, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The majority of antiviral therapeutics target conserved viral proteins, however, this approach confers selective pressure on the virus and increases the probability of antiviral drug resistance. An alternative therapeutic strategy is to target the host-encoded factors that are required for virus inf...