Improvement in the dissolution rate and tableting properties of cefuroxime axetil by melt-granulated dispersion and surface adsorption

• Main Authors: Jammula Sruti (Author), Chinam Niranjan Patra (Author), Suryakanta Swain (Author), Kanhu Charan Panigrahi (Author), Allupati Premananda Patro (Author), Sarwar Beg (Author), Subas Chandra Dinda (Author), Muddana Eswara Bhanoji Rao (Author)
• Format: Book
• Published: Elsevier, 2013-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A combination of melt-granulated dispersion and surface adsorption techniques was used to enhance the dissolution and tableting properties of cefuroxime axetil (CA). Gelucire 50/13 was used as the melt-dispersion carrier and Sylysia 350 was used to adsorb the melt dispersion. Solubility studies show...