Ceftazidime-avibactam treatment dilemma of bla KPC−2-containing Klebsiella pneumoniae due to the development of co-existence of mixed strains carrying bla KPC−2 or bla KPC−33 in lung transplant recipients

• Main Authors: Zichen Lei (Author), Ziyao Li (Author), Yulin Zhang (Author), Lingbing Zeng (Author), Yongli Wu (Author), Feilong Zhang (Author), Xinrui Yang (Author), Xinmeng Liu (Author), Qi Liu (Author), Yiqun Ma (Author), Binghuai Lu (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant threat to immunocompromised populations, including lung transplant recipients. This study investigates mixed CRKP strains carrying either bla KPC−2 or bla KPC−33 following ceftazidime-avibactam (CAZ/AVI) exposu...