Identification and detection of a novel point mutation in the Chitin Synthase gene of Culex pipiens associated with diflubenzuron resistance.

• Main Authors: Emmanouil A Fotakis (Author), Valentina Mastrantonio (Author), Linda Grigoraki (Author), Daniele Porretta (Author), Arianna Puggioli (Author), Alexandra Chaskopoulou (Author), Hugo Osório (Author), Mylène Weill (Author), Romeo Bellini (Author), Sandra Urbanelli (Author), John Vontas (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Diflubenzuron (DFB) is one of the most used insecticides in mosquito larval control including that of Culex pipiens, the proven vector of the recent West Nile Virus epidemics in Europe. Two mutations (I1043L and I1043M) in the chitin synthase (CHS) putative binding site of DFB have been p...