Autoantibody of NRIP, a novel AChR‐interacting protein, plays a detrimental role in myasthenia gravis

• Main Authors: Li‐Kai Tsai (Author), I‐Hsin Chen (Author), Chi‐Chao Chao (Author), Hsueh‐Wen Hsueh (Author), Hsin‐Hsiung Chen (Author), Yun‐Hsin Huang (Author), Rong‐Wei Weng (Author), Tzu‐Yun Lai (Author), Yi‐Chieh Tsai (Author), Yeou‐Ping Tsao (Author), Show‐Li Chen (Author)
• Format: Book
• Published: Wiley, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Nuclear receptor interaction protein (NRIP) co‐localizes with acetylcholine receptor (AChR) at the neuromuscular junction (NMJ), and NRIP deficiency causes aberrant NMJ architecture. However, the normal physiological and pathophysiological roles of NRIP in NMJ are still unclear....