Nuciferine downregulates Per-Arnt-Sim kinase expression during its alleviation of lipogenesis and inflammation on oleic acid-induced hepatic steatosis in HepG2 cells

• Main Authors: Dan-dan eZhang (Author), Ji-gang eZhang (Author), Xin eWu (Author), Ying eLiu (Author), Sheng-ying eGu (Author), Guan-hua eZhu (Author), Yu-zhu eWang (Author), Gao-lin eLiu (Author), Xiao-Yu eLi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nonalcoholic fatty liver disease (NAFLD) is a prevalent liver disease associated with lipotoxicity, lipid peroxidation, oxidative stress and inflammation. Nuciferine, an active ingredient extracted from the natural lotus leaf, has been reported to be effective for the prevention and treatment of NAF...