Exposure‐safety and exposure‐efficacy analyses for tisotumab vedotin for patients with locally advanced or metastatic solid tumors

• Main Authors: Chaitali Passey (Author), Jenna Voellinger (Author), Leonid Gibiansky (Author), Rudy Gunawan (Author), Leonardo Nicacio (Author), Ibrahima Soumaoro (Author), William D. Hanley (Author), Helen Winter (Author), Manish Gupta (Author)
• Format: Book
• Published: Wiley, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The antibody‐drug conjugate (ADC) tisotumab vedotin (TV) received accelerated approval from the US Food and Drug Administration for treatment of adults with recurrent or metastatic cervical cancer (r/mCC) with disease progression on or after chemotherapy. A population pharmacokinetic (PK) m...