Participation of PKG and PKA-related pathways in the IFN-γ induced modulation of the BKCa channel activity in human cardiac fibroblasts

• Main Authors: M.V. Mitrokhin (Author), V. Kalsin (Author), O. Kamkina (Author), I. Babkina (Author), A. Zotov (Author), V.A. Troitskiy (Author), M.I. Mladenov (Author), G.A. Kamkin (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study was devoted to elucidating the interferon (IFN)-γ-induced signaling pathway and the interaction between protein kinase G (PKG) and protein kinase A (PKA) through large-conductance Ca(2+)-activated K(+) channels in human cardiac fibroblasts. The IK currents were recorded using a whole-cell...