Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes

• Main Authors: Hiroyuki Mori (Author), Sydney K. Peterson (Author), Rachel C. Simmermon (Author), Katherine A. Overmyer (Author), Akira Nishii (Author), Emma Paulsson (Author), Ziru Li (Author), Annie Jen (Author), Romina M. Uranga (Author), Jessica N. Maung (Author), Warren T. Yacawych (Author), Kenneth T. Lewis (Author), Rebecca L. Schill (Author), Taryn Hetrick (Author), Ryo Seino (Author), Ken Inoki (Author), Joshua J. Coon (Author), Ormond A. MacDougald (Author)
• Format: Book
• Published: Elsevier, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Exposure of adipocytes to 'cool' temperatures often found in the periphery of the body induces expression of Stearoyl-CoA Desaturase-1 (Scd1), an enzyme that converts saturated fatty acids to monounsaturated fatty acids. The goal of this study is to further investigate the roles...