In vitro effect of nicorandil on the carbachol-induced contraction of the lower esophageal sphincter of the rat
The lower esophageal sphincter (LES) is a specialized region of the esophageal smooth muscle that allows the passage of a swallowed bolus into the stomach. Nitric oxide (NO) plays a major role in LES relaxation. Nicorandil possesses dual properties of a NO donor and an ATP-sensitive potassium channe...
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| Main Authors: | , , , , , |
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| Format: | Book |
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Elsevier,
2016-08-01T00:00:00Z.
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