Chemokine levels predict progressive liver disease in Down syndrome patients with transient abnormal myelopoiesis

• Main Authors: Tadamune Kinjo (Author), Hirosuke Inoue (Author), Takeshi Kusuda (Author), Junko Fujiyoshi (Author), Masayuki Ochiai (Author), Yasushi Takahata (Author), Satoshi Honjo (Author), Yuhki Koga (Author), Toshiro Hara (Author), Shouichi Ohga (Author)
• Format: Book
• Published: Elsevier, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Transient abnormal myelopoiesis (TAM) is a neonatal preleukemic syndrome that occurs exclusively in neonates with Down syndrome (DS). Most affected infants spontaneously resolve, although some patients culminate in hepatic failure despite the hematological remission. It is impossible to...