Selenium participates in the formation of kidney stones by alleviating endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells

• Main Authors: Xiaozhe Su (Author), Hongbo Chen (Author), Heng Xiang (Author), Hu Ke (Author), Caitao Dong (Author), Qianlin Song (Author), Jiawei Zhou (Author), Qinhong Jiang (Author), Yunhan Wang (Author), Liang Chen (Author), Sixing Yang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: To investigate the role of selenium and selenium-containing proteins in the etiology and pathogenesis of kidney stones.Methods: The HK-2 cell line was subjected to supersaturation oxalate treatment to establish an in vitro model of calcium oxalate kidney stones, while SD rats were admini...