Bacterial magnetic particles improve testes-mediated transgene efficiency in mice

• Main Authors: Chao Wang (Author), Guanghong Sun (Author), Ye Wang (Author), Nana Kong (Author), Yafei Chi (Author), Leilei Yang (Author), Qiliang Xin (Author), Zhen Teng (Author), Xu Wang (Author), Yujun Wen (Author), Ying Li (Author), Guoliang Xia (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nano-scaled materials have been proved to be ideal DNA carriers for transgene. Bacterial magnetic particles (BMPs) help to reduce the toxicity of polyethylenimine (PEI), an efficient gene-transferring agent, and assist tissue transgene ex vivo. Here, the effectiveness of the BMP-PEI complex-conjugat...