ZCCHC8 p.P410A disrupts nucleocytoplasmic localization, promoting idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease

• Main Authors: Chen-Yu Wang (Author), Si-Hua Chang (Author), Cheng-Feng Hu (Author), Yi-Qiao Hu (Author), Hong Luo (Author), Lv Liu (Author), Liang-Liang Fan (Author)
• 格式: 圖書
• 出版: BMC, 2024-09-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a special kind of chronic interstitial lung disease with insidious onset. Previous studies have revealed that mutations in ZCCHC8 may lead to IPF. The aim of this study is to explore the ZCCHC8 mutations in Chinese IPF patients. Methods Here...