Oxidant/Antioxidant Status Is Impaired in Sepsis and Is Related to Anti-Apoptotic, Inflammatory, and Innate Immunity Alterations

• Main Authors: Marianna Miliaraki (Author), Panagiotis Briassoulis (Author), Stavroula Ilia (Author), Kalliopi Michalakakou (Author), Theodoros Karakonstantakis (Author), Aikaterini Polonifi (Author), Kalliopi Bastaki (Author), Efrossini Briassouli (Author), Konstantinos Vardas (Author), Aikaterini Pistiki (Author), Maria Theodorakopoulou (Author), Theonymfi Tavladaki (Author), Anna-Maria Spanaki (Author), Eumorfia Kondili (Author), Helen Dimitriou (Author), Maria Venihaki (Author), Sotirios Tsiodras (Author), Dimitrios Georgopoulos (Author), Marina Mantzourani (Author), Serafeim Nanas (Author), Apostolos Armaganidis (Author), George L. Daikos (Author), Ioannis Papassotiriou (Author), George Briassoulis (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress is considered pivotal in the pathophysiology of sepsis. Oxidants modulate heat shock proteins (Hsp), interleukins (IL), and cell death pathways, including apoptosis. This multicenter prospective observational study was designed to ascertain whether an oxidant/antioxidant imbalance i...