A six-generation Chinese family in haplogroup B4C1C exhibits high penetrance of 1555A > G-induced hearing Loss

• Main Authors: Bai Yan (Author), Wang Zhengmin (Author), Dai Wenjia (Author), Li Qingzhong (Author), Chen Guoling (Author), Cong Ning (Author), Guan Minxin (Author), Li Huawei (Author)
• Format: Book
• Published: BMC, 2010-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The 1555A > G mutation is the most common cause of aminoglycoside-induced and non-syndromic deafness. However, the variable clinical phenotype and incomplete penetrance of A1555G-induced hearing loss complicate our understanding o...