A six-generation Chinese family in haplogroup B4C1C exhibits high penetrance of 1555A > G-induced hearing Loss

• Autors principals: Bai Yan (Autor), Wang Zhengmin (Autor), Dai Wenjia (Autor), Li Qingzhong (Autor), Chen Guoling (Autor), Cong Ning (Autor), Guan Minxin (Autor), Li Huawei (Autor)
• Format: Llibre
• Publicat: BMC, 2010-09-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The 1555A > G mutation is the most common cause of aminoglycoside-induced and non-syndromic deafness. However, the variable clinical phenotype and incomplete penetrance of A1555G-induced hearing loss complicate our understanding o...