Discovery of Novel Myristic Acid Derivatives as N-Myristoyltransferase Inhibitors: Design, Synthesis, Analysis, Computational Studies and Antifungal Activity

• Main Authors: Saleem Javid (Author), Hissana Ather (Author), Umme Hani (Author), Ayesha Siddiqua (Author), Shaik Mohammad Asif Ansari (Author), Dhivya Shanmugarajan (Author), Honnavalli Yogish Kumar (Author), Rajaguru Arivuselvam (Author), Madhusudan N. Purohit (Author), B. R. Prashantha Kumar (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In recent years, N-Myristoyltransferase (NMT) has been identified as a new target for the treatment of fungal infections. It is observed that at present, there are increased rates of morbidity and mortality due to fungal infections. Hence, a series of novel myristic acid derivatives were designed vi...