Involvement of Carboxylesterase in Hydrolysis of Propranolol Prodrug during Permeation across Rat Skin
The use of a prodrug, a conjugate of an active drug with a lipophilic substituent, is a good way of increasing the cutaneous absorption of a drug. However, the activity of dermal hydrolases has rarely been investigated in humans, or experimental animals. In the present study, we focused on the ident...
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Format: | Book |
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MDPI AG,
2013-07-01T00:00:00Z.
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Call Number: |
A1234.567 |
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Copy 1 | Available |