The Challenge of Targeting Notch in Hematologic Malignancies

Notch signaling can play oncogenic and tumor suppressor roles depending on cell type. Hematologic malignancies encompass a wide range of transformed cells, and consequently the roles of Notch are diverse in these diseases. For example Notch is a potent T cell oncogene, with >50% of T cell acute l...

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Main Authors: Fiorela N Hernandez Tejada (Author), Jorge R Galvez Silva (Author), Patrick A Zweidler-Mckay (Author)
Format: Book
Published: Frontiers Media S.A., 2014-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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