The Challenge of Targeting Notch in Hematologic Malignancies
Notch signaling can play oncogenic and tumor suppressor roles depending on cell type. Hematologic malignancies encompass a wide range of transformed cells, and consequently the roles of Notch are diverse in these diseases. For example Notch is a potent T cell oncogene, with >50% of T cell acute l...
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| Main Authors: | , , |
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| Format: | Book |
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Frontiers Media S.A.,
2014-06-01T00:00:00Z.
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