Artificial Intelligence and Machine Learning Models for Predicting Drug-Induced Kidney Injury in Small Molecules

• Main Authors: Mohan Rao (Author), Vahid Nassiri (Author), Sanjay Srivastava (Author), Amy Yang (Author), Satjit Brar (Author), Eric McDuffie (Author), Clifford Sachs (Author)
• Format: Book
• Published: MDPI AG, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Objectives: Drug-Induced Kidney Injury (DIKI) presents a significant challenge in drug development, often leading to clinical-stage failures. The early prediction of DIKI risk can improve drug safety and development efficiency. Existing models tend to focus on physicochemical properties a...