Artificial Intelligence and Machine Learning Models for Predicting Drug-Induced Kidney Injury in Small Molecules

• Główni autorzy: Mohan Rao (Autor), Vahid Nassiri (Autor), Sanjay Srivastava (Autor), Amy Yang (Autor), Satjit Brar (Autor), Eric McDuffie (Autor), Clifford Sachs (Autor)
• Format: Książka
• Wydane: MDPI AG, 2024-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background/Objectives: Drug-Induced Kidney Injury (DIKI) presents a significant challenge in drug development, often leading to clinical-stage failures. The early prediction of DIKI risk can improve drug safety and development efficiency. Existing models tend to focus on physicochemical properties a...