Probucol ameliorates hepatic stellate cell activation and autophagy is associated with farnesoid X receptor

• Main Authors: Ruhui Yang (Author), Zhiyong Hu (Author), Pengyong Zhang (Author), Songquan Wu (Author), Zhaoxia Song (Author), Xiangchun Shen (Author), Zhe Wei (Author)
• Format: Book
• Published: Elsevier, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Probucol has antioxidant effects and inhibits inflammation. Farnesoid X receptor (FXR) is a nuclear receptor that regulates autophagy, which is regarded as the key cause of the activation of hepatic stellate cell (HSC). In this study, the effects of probucol on HSC activation and autophagy in vitro...