Interferon-γ Is a Crucial Activator of Early Host Immune Defense against Mycobacterium ulcerans Infection in Mice.

• Auteurs principaux: Raphael Bieri (Auteur), Miriam Bolz (Auteur), Marie-Thérèse Ruf (Auteur), Gerd Pluschke (Auteur)
• Format: Livre
• Publié: Public Library of Science (PLoS), 2016-02-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Buruli ulcer (BU), caused by infection with Mycobacterium ulcerans, is a chronic necrotizing human skin disease associated with the production of the cytotoxic macrolide exotoxin mycolactone. Despite extensive research, the type of immune responses elicited against this pathogen and the effector fun...