Crystal structure-guided design of berberine-based novel chitinase inhibitors

Glycoside hydrolase family 18 (GH18) chitinases play an important role in various organisms ranging from bacteria to mammals. Chitinase inhibitors have potential applications as pesticides, fungicides, and anti-asthmatics. Berberine, a plant-derived isoquinoline alkaloid, was previously reported to...

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Main Authors: Lei Chen (Author), Ling Zhu (Author), Jinli Chen (Author), Wei Chen (Author), Xuhong Qian (Author), Qing Yang (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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