Development of an Antibody Delivery Method for Cancer Treatment by Combining Ultrasound with Therapeutic Antibody-Modified Nanobubbles Using Fc-Binding Polypeptide

• Main Authors: Yusuke Yano (Author), Nobuhito Hamano (Author), Kenshin Haruta (Author), Tomomi Kobayashi (Author), Masahiro Sato (Author), Yamato Kikkawa (Author), Yoko Endo-Takahashi (Author), Rui Tada (Author), Ryo Suzuki (Author), Kazuo Maruyama (Author), Motoyoshi Nomizu (Author), Yoichi Negishi (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A key challenge in treating solid tumors is that the tumor microenvironment often inhibits the penetration of therapeutic antibodies into the tumor, leading to reduced therapeutic efficiency. It has been reported that the combination of ultrasound-responsive micro/nanobubble and therapeutic ultrasou...