The crosstalk of ABCA1 and ANXA1: a potential mechanism for protection against atherosclerosis

• Principais autores: Xin Shen (Autor), Shun Zhang (Autor), Zhu Guo (Autor), Dongming Xing (Autor), Wujun Chen (Autor)
• Formato: Livro
• Publicado em: BMC, 2020-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occu...