Trioleyl Pyridinium, a Cationic Transfection Agent for the Lipofection of Therapeutic Oligonucleotides into Mammalian Cells

• Main Authors: Ana Delgado (Author), Rosa Griera (Author), Núria Llor (Author), Ester López-Aguilar (Author), Maria Antònia Busquets (Author), Véronique Noé (Author), Carlos J. Ciudad (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: One of the most significant limitations that therapeutic oligonucleotides present is the development of specific and efficient delivery vectors for the internalization of nucleic acids into cells. Therefore, there is a need for the development of new transfection agents that ensure a pro...