Changes in Characteristics of the Specific Binding of [3H]LY-278584, a 5-HT3-Receptor Antagonist, on Differentiated NG108-15 Cells

• Main Authors: Kayoko Matsushima (Author), Takashi Imanishi (Author), Hajime Asano (Author), Yoshinori Funakami (Author), Tetsuyuki Wada (Author), Seiji Ichida (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We have reported previously that the concentration of intracellular Ca2+ evoked by serotonin (5-HT) was significantly augmented in differentiated NG108-15 (NG) cells treated with dibutyryl cAMP and the enhanced response occurred via 5-HT3 receptors. We investigated changes in the characteristics for...