Designing Stable <i>Bacillus anthracis</i> Antigens with a View to Recombinant Anthrax Vaccine Development

• Main Authors: Ekaterina M. Ryabchevskaya (Author), Dmitriy L. Granovskiy (Author), Ekaterina A. Evtushenko (Author), Peter A. Ivanov (Author), Olga A. Kondakova (Author), Nikolai A. Nikitin (Author), Olga V. Karpova (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Anthrax is a disease caused by <i>Bacillus anthracis</i> that affects mammals, including humans. Recombinant <i>B. anthracis</i> protective antigen (rPA) is the most common basis for modern anthrax vaccine candidates. However, this protein is characterised by low stability du...