A Candidate Gene Approach to ANCA-Associated Vasculitis Reveals Links to the C3 and CTLA-4 Genes but not to the IL1-Ra And Fcγ-RIIa Genes

• Main Authors: Ulf Persson (Author), Birgitta Gullstrand (Author), Åsa Pettersson (Author), Gunnar Sturfelt (Author), Lennart Truedsson (Author), Mårten Segelmark (Author)
• Format: Book
• Published: Karger Publishers, 2013-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: The aim of the study is to search for associations between Antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) and polymorphisms in the genes of four key molecules possibly involved in different pathogenic pathways; complement C3, CTLA-4, Fcγ-RIIa and IL1-Ra. Patien...