Effects of psilocybin, psychedelic mushroom extract and 5-hydroxytryptophan on brain immediate early gene expression: Interaction with serotonergic receptor modulators

• Main Authors: Elad Lerer (Author), Alexander Botvinnik (Author), Orr Shahar (Author), Meitar Grad (Author), Karin Blakolmer (Author), Noam Shomron (Author), Amit Lotan (Author), Bernard Lerer (Author), Tzuri Lifschytz (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Immediate early genes (IEGs) are rapidly activated and initiate diverse cellular processes including neuroplasticity. We report the effect of psilocybin (PSIL), PSIL-containing psychedelic mushroom extract (PME) and 5-hydroxytryptophan (5-HTP) on expression of the IEGs, cfos, egr1, and e...