Coadministration of the Three Antigenic Leishmania infantum Poly (A) Binding Proteins as a DNA Vaccine Induces Protection against Leishmania major Infection in BALB/c Mice.

• Main Authors: Manuel Soto (Author), Laura Corvo (Author), Esther Garde (Author), Laura Ramírez (Author), Virginia Iniesta (Author), Pedro Bonay (Author), Carlos Gómez-Nieto (Author), Víctor M González (Author), M Elena Martín (Author), Carlos Alonso (Author), Eduardo A F Coelho (Author), Aldina Barral (Author), Manoel Barral-Netto (Author), Salvador Iborra (Author)
• 格式: 圖書
• 出版: Public Library of Science (PLoS), 2015-05-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

BACKGROUND:Highly conserved intracellular proteins from Leishmania have been described as antigens in natural and experimental infected mammals. The present study aimed to evaluate the antigenicity and prophylactic properties of the Leishmania infantum Poly (A) binding proteins (LiPABPs). METHODOLOG...