Computational and experimental pharmacology to decode the efficacy of Theobroma cacao L. against doxorubicin-induced organ toxicity in EAC-mediated solid tumor-induced mice

• Main Authors: Priyanka P. Patil (Author), Pranjal Kumar (Author), Pukar Khanal (Author), Vishal S. Patil (Author), Harish R. Darasaguppe (Author), Vishwambhar Vishnu Bhandare (Author), Arati Bhatkande (Author), Sudhanshu Shukla (Author), Rajesh K. Joshi (Author), Basanagouda M. Patil (Author), Subarna Roy (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and objective: Doxorubicin is extensively utilized chemotherapeutic drug, and it causes damage to the heart, liver, and kidneys through oxidative stress. Theobroma cacao L (cocoa) is reported to possess protective effects against several chemical-induced organ damages and also acts as an...