Predicting treatment response to vancomycin using bacterial DNA load as a pharmacodynamic marker in premature and very low birth weight neonates: A population PKPD study

• Үндсэн зохиолчид: Amadou Samb (Зохиогч), Rimke De Kroon (Зохиогч), Koos Dijkstra (Зохиогч), Marre Van Den Brand (Зохиогч), Martine Bos (Зохиогч), Frank Van Den Dungen (Зохиогч), Agnes Veldkamp (Зохиогч), Bram Wilhelm (Зохиогч), Timo R. De Haan (Зохиогч), Yuma A. Bijleveld (Зохиогч), Marceline Tutu Van Furth (Зохиогч), Paul Savelkoul (Зохиогч), Noortje Swart (Зохиогч), Ron Mathot (Зохиогч), Mirjam Van Weissenbruch (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Background: While positive blood cultures are the gold standard for late-onset sepsis (LOS) diagnosis in premature and very low birth weight (VLBW) newborns, these results can take days, and early markers of possible treatment efficacy are lacking. The objective of the present study was to investiga...