Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes

• Main Authors: Didier F. Pisani (Author), Valentin Barquissau (Author), Jean-Claude Chambard (Author), Diane Beuzelin (Author), Rayane A. Ghandour (Author), Maude Giroud (Author), Aline Mairal (Author), Sophie Pagnotta (Author), Saverio Cinti (Author), Dominique Langin (Author), Ez-Zoubir Amri (Author)
• Format: Book
• Published: Elsevier, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Thermogenic adipocytes (i.e. brown or brite/beige adipocytes) are able to burn large amounts of lipids and carbohydrates as a result of highly active mitochondria and enhanced uncoupled respiration, due to UCP1 activity. Although mitochondria are the key organelles for this thermogenic fu...