The Cytochrome P450-Mediated Metabolism Alternation of Four Effective Lignans From Schisandra chinensis in Carbon Tetrachloride-Intoxicated Rats and Patients With Advanced Hepatocellular Carcinoma

• Autors principals: Rongrong Wu (Autor), Zhiyong Xiao (Autor), Xiaorui Zhang (Autor), Feng Liu (Autor), Wenxia Zhou (Autor), Yongxiang Zhang (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

It is highly valuable to study the pharmacokinetics of herbal components under the pathological condition of liver dysfunction for safe and rational use of herbal medicines. In this study, the pharmacokinetic profiles of four effective lignans from Schisandra chinensis (SC), schisandrin, schisanther...