IN VITRO ABSORPTION STUDY OF CARBAMAZEPINE SOLID DISPERSION USING EVERTED GUT SAC METHOD

• Main Authors: Nishant Thakur (Author), Sunil Thakral (Author), Manish Goswami (Author), Pankaj Ghaie (Author), Amit Thakur (Author), Mohit Mangal (Author)
• Format: Book
• Published: Universitas Gadjah Mada, 2013-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The oral Bioavailability of BCS (Bio Pharmaceutical Classification System) class II drug with poor solubility and reasonable permeability is limited by drug dissolution. In order to improve the aqueous solubility of the drug and dissolution of thedrug, the solid dispersion was prepared and evaluated...