Novel genetic alterations in liver cancer distinguish distinct clinical outcomes and combination immunotherapy responses

• Main Authors: Yizhou Wang (Author), Peipei Shang (Author), Chang Xu (Author), Wei Dong (Author), Xiaofeng Zhang (Author), Yong Xia (Author), Chengjun Sui (Author), Cheng Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Genomic profiling has revolutionized therapeutic interventions and the clinical management of liver cancer. However, pathogenetic mechanisms, molecular determinants of recurrence, and predictive biomarkers for first-line treatment (anti-PD-(L)1 plus bevacizumab) in liver cancer remain...