MDMA Impairs Response to Water Intake in Healthy Volunteers

• Egile Nagusiak: Matthew J. Baggott (Egilea), Kathleen J. Garrison (Egilea), Jeremy R. Coyle (Egilea), Gantt P. Galloway (Egilea), Allan J. Barnes (Egilea), Marilyn A. Huestis (Egilea), John E. Mendelson (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi Limited, 2016-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Hyponatremia is a serious complication of 3,4-methylenedioxymethamphetamine (MDMA) use. We investigated potential mechanisms in two double-blind, placebo-controlled studies. In Study 1, healthy drug-experienced volunteers received MDMA or placebo alone and in combination with the alpha-1 adrenergic...