Combined antitumoral effects of pretubulysin and methotrexate

• Asıl Yazarlar: Sarah Kern (Yazar), Ines Truebenbach (Yazar), Miriam Höhn (Yazar), Jan Gorges (Yazar), Uli Kazmaier (Yazar), Stefan Zahler (Yazar), Angelika M. Vollmar (Yazar), Ernst Wagner (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2019-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Pretubulysin (PT), a potent tubulin‐binding antitumoral drug, and the well‐established antimetabolite methotrexate (MTX) were tested separately or in combination (PT+MTX) for antitumoral activity in L1210 leukemia cells or KB cervix carcinoma cells in vitro and in vivo in NMRI‐nu/nu tumor m...