The Efficacy and Safety of Polyethylene Glycol Cholesterol- and Tocopherol Polyethylene Glycol 1000 Succinate-Modified Transforming Growth Factor β1 Small Interfering RNA Lipid Nanoparticles in the Treatment of Paclitaxel-Resistant Non-Small-Cell Lung Cancer

• Главные авторы: Zhaowu Zeng (Автор), Xianglong Zeng (Автор), Xinyi Li (Автор), Yuxin Feng (Автор), Yue Kan (Автор), Xingyan Liu (Автор), Yiying Zeng (Автор)
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• Опубликовано: MDPI AG, 2024-01-01T00:00:00Z.
• Предметы: article
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The aim of this study was to explore the efficacy and safety of TGFβ1 siRNA lipid nanoparticles (LNPs) modified with different PEG derivatives (PEG5000 cholesterol, abbreviated as CE; tocopherol polyethylene glycol 1000 succinate, abbreviated as TPGS) in the treatment of paclitaxel-resistant non-sma...