RhoA Promotes Synovial Proliferation and Bone Erosion in Rheumatoid Arthritis through Wnt/PCP Pathway

• Main Authors: Ning Chen (Author), Chao-Yue Diao (Author), Xin Huang (Author), Wei-Xing Tan (Author), Ya-Bing Chen (Author), Xin-Yu Qian (Author), Jie Gao (Author), Dong-Bao Zhao (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ras homolog gene family member A (RhoA) plays a major role in the Wnt/planar cell polarity (PCP) pathway, which is significantly activated in patients with rheumatoid arthritis (RA). The function of RhoA in RA synovitis and bone erosion is still elusive. Here, we not only explored the impact of RhoA...