Suggestive evidence of associations between liver X receptor β polymorphisms with type 2 diabetes mellitus and obesity in three cohort studies: HUNT2 (Norway), MONICA (France) and HELENA (Europe)

• Main Authors: Dallongeville Jean (Author), Ruiz Jonatan R (Author), Widhalm Kurt (Author), Valtueña Jara (Author), Romeo Javier (Author), Lien Sigbjorn (Author), Amouyel Philippe (Author), Ferrières Jean (Author), Holven Kirsten B (Author), Berg Paul R (Author), Retterstol Kjetil (Author), Legry Vanessa (Author), Solaas Karianne (Author), Tonstad Serena (Author), Rootwelt Helge (Author), Halvorsen Bente (Author), Nenseter Marit S (Author), Birkeland Kare I (Author), Thorsby Per M (Author), Meirhaeghe Aline (Author), Nebb Hilde I (Author)
• Format: Book
• Published: BMC, 2010-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The liver X receptors (LXR) α and β regulate lipid and carbohydrate homeostasis and inflammation. <it>Lxrβ</it>^{<it>-/- </it>}mice are glucose intolerant and at the same time lean. We aime...