Withania somnifera modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC's)

• Autori principali: Dhaneshree Bestinee Naidoo (Autore), Anil Amichund Chuturgoon (Autore), Alisa Phulukdaree (Autore), Kanive Parashiva Guruprasad (Autore), Kapaettu Satyamoorthy (Autore), Vikash Sewram (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2018-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Cancer and inflammation are associated with cachexia. Withania somnifera (W. somnifera) possesses antioxidant and anti-inflammatory potential. We investigated the potential of an aqueous extract of the root of W. somnifera (WRE) to modulate cytokines, antioxidants and apoptosis i...