Withania somnifera modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC's)

• Main Authors: Dhaneshree Bestinee Naidoo (Author), Anil Amichund Chuturgoon (Author), Alisa Phulukdaree (Author), Kanive Parashiva Guruprasad (Author), Kapaettu Satyamoorthy (Author), Vikash Sewram (Author)
• Format: Book
• Published: BMC, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer and inflammation are associated with cachexia. Withania somnifera (W. somnifera) possesses antioxidant and anti-inflammatory potential. We investigated the potential of an aqueous extract of the root of W. somnifera (WRE) to modulate cytokines, antioxidants and apoptosis i...