Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death

• Asıl Yazarlar: Mathieu eBourdenx (Yazar), Erwan eBezard (Yazar), Benjamin eDehay (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2014-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Neurodegenerative diseases are (i) characterized by a selective neuronal vulnerability to degeneration in specific brain regions and (ii) likely to be caused by disease-specific protein misfolding. Parkinson's disease (PD) is characterized by the presence of intraneuronal proteinacious cytoplas...