Dual-responsive nanosystem based on TGF-β blockade and immunogenic chemotherapy for effective chemoimmunotherapy

• Main Authors: Xiaoxian Huang (Author), Lingfei Han (Author), Ruyi Wang (Author), Wanfang Zhu (Author), Ning Zhang (Author), Wei Qu (Author), Wenyuan Liu (Author), Fulei Liu (Author), Feng Feng (Author), Jingwei Xue (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The antitumor immune response induced by chemotherapy has attracted considerable attention. However, the immunosuppressive tumor microenvironment hinders the immune activation effect of cancer chemotherapy. TGF-β plays a key role in driving tumor immunosuppression and can prevent effective antitumor...