Costimulation of Murine Osteoblasts with Interferon-γ and Tumor Necrosis Factor-α Induces Apoptosis through Downregulation of Bcl-2 and Release of Cytochrome c from Mitochondria

During chronic inflammation from diseases, such as periodontal disease, the proinflammatory cytokines interferon-gamma (IFNγ) and tumor necrosis factor-α (TNFα) alter bone remodeling. To elucidate the underlying molecular mechanisms, we investigated the effect of IFNγ and TNFα on the proliferation a...

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Main Authors: Mayumi Iguchi (Author), Miki Hiroi (Author), Haruhide Kanegae (Author), Yoshihiro Ohmori (Author)
Format: Book
Published: Hindawi Limited, 2018-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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