A Novel Cardenolide Glycoside Isolated from <i>Xysmalobium undulatum</i> Reduces Levels of the Alzheimer's Disease-Associated β-Amyloid Peptides Aβ42 In Vitro

• Egile Nagusiak: Anuradha Thakur (Egilea), Phanankosi Moyo (Egilea), Carl Johan van der Westhuizen (Egilea), Hyun Ok Yang (Egilea), Vinesh Maharaj (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2021-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Elevated levels of the amylo β-proteins (Aβ), particularly Aβ42, are associated with a high risk of Alzheimer's disease (AD). The Aβ proteins are produced from cellular processing of the amyloid precursor proteins (APPs). To identify natural products that block the formation of Aβ-proteins from...