Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine

Strengthening of immunodominance hierarchy of influenza subtype-specific neutralizing antibody response by annual polyvalent vaccinations could increase the variation of vaccine effectiveness by subtype. Therefore, we suggest the assessment of neutralizing antibody titer prior to seasonal vaccinatio...

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Bibliographic Details
Main Authors: Hoyoung Lee (Author), Eun Hyoung Shim (Author), Sooseong You (Author)
Format: Book
Published: Taylor & Francis Group, 2018-10-01T00:00:00Z.
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Summary:Strengthening of immunodominance hierarchy of influenza subtype-specific neutralizing antibody response by annual polyvalent vaccinations could increase the variation of vaccine effectiveness by subtype. Therefore, we suggest the assessment of neutralizing antibody titer prior to seasonal vaccination and recommend the inoculation of only strains lower than protective levels.
Item Description:2164-5515
2164-554X
10.1080/21645515.2018.1482172