Analysis of intracellular tyrosine phosphorylation in circulating neutrophils as a rapid assay for the in vivo effect of oral tyrosine kinase inhibitors

Tyrosine kinases are crucial signaling components of diverse biological processes and are major therapeutic targets in various malignancies and immune-mediated disorders. A critical step of development of novel tyrosine kinase inhibitors is the transition from the confirmation of the in vitro effect...

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Main Authors: Krisztina Futosi (Author), Boglárka Bajza (Author), Dorottya Deli (Author), András Erdélyi (Author), Simon Tusnády (Author), Attila Mócsai (Author)
Format: Book
Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
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3rd Floor Main Library

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